The SN74AVC4T774 device uses two separate configurable power-supply rails, V_CCA and V_CCB. V_CCA accepts any supply voltage from 1.1V to 3.6V and V_CCB accepts any supply voltage from 1.1V to 3.6V. The A port and B port are designed to track V_CCA and V_CCB respectively allowing for low-voltage, bi-directional translation between any of the 1.2V, 1.5V, 1.8V, 2.5V and 3.3V voltage nodes.

The output-enable OE input circuit is designed so that it is supplied by V_CCA and when the OE input is high, all outputs are placed in the high-impedance state. To ensure the high-impedance state of the outputs during power-up or power-down, the OE input pin must be tied to V_CCA through a pullup resistor and must not be enabled until V_CCA and V_CCB are fully ramped and stable. The minimum value of the pullup resistor to V_CCA is determined by the current-sinking capability of the driver.