The TLV2553 is designed to operate from a single power supply voltage from 2.7 V ti 5.5 V. The ADC supply voltage must be well-regulated. A 1-μF ceramic decoupling capacitor is required and must be placed as close as possible to the device to minimize inductance along the load current path.

Many modern microcontrollers have interfaces that support only up to 3.3-V logic levels, which is incompatible with the TLV2553 when the device is operated on a 5-V power supply. In such cases, 5-V to 3.3-V digital level translators may be used to facilitate communication between the TLV2553 and the microcontroller host.