The normal operation of the application is to take multiple differential inputs and use a multi-channel switch to pass the signal to the downstream instrumentation amplifier. A fault protected switch can add extra robustness to the sytem against fault conditions while also reducing the number of components required to interface with the systems physical input channels.

The previous image shows the case where a human wired the condition incorrectly and one of the input connectors shorted to the power board supply voltage. If the board supply voltage is higher than the power supply of the multiplexer, then the TMUX741xF device will disconnect the source input from passing the signal to protect the downstream components. The drain pin of the mux channels under fault will be left floating.