A typical application for TUSB216 is shown in Figure 8-1. In this setup, D2P and D2M face the USB connector while D1P and D1M face the USB host. The orientation may be reversed [that is, D2 faces transceiver and D1 faces connector].

Figure 8-1 TUSB216 Reference Schematic (Design Example with CDP disabled), CDP_ENZ Can Be Left Floating but an Option for a Decoupling Capacitor of 0.1 µF is Recommended So the Design is Compatible with Older Devices: TUSB211, TUSB212, TUSB214