The input pins (IN+ and IN–) of the UCC53x0 family are based on CMOS-compatible input-threshold logic that is completely isolated from the V_CC2 supply voltage. The input pins are easy to drive with logic-level control signals (such as those from 3.3-V microcontrollers), because the UCC53x0 family has a typical high threshold (V_IT+(IN)) of 0.55 × V_CC1 and a typical low threshold of 0.45 × V_CC1. A wide hysteresis (V_hys(IN)) of 0.1 × V_CC1 makes for good noise immunity and stable operation. If either of the inputs are left open, 128 kΩ of internal pull-down resistance forces the IN+ pin low and 128 kΩ of internal resistance pulls IN– high. However, TI still recommends grounding an input or tying to VCC1 if it is not being used for improved noise immunity.

Because the input side of the UCC53x0 family is isolated from the output driver, the input signal amplitude can be larger or smaller than V_CC2 provided that it does not exceed the recommended limit. This feature allows greater flexibility when integrating the gate-driver with control signal sources and allows the user to choose the most efficient V_CC2 for any gate. However, the amplitude of any signal applied to IN+ or IN– must never be at a voltage higher than V_CC1.