The LMK03328 incorporates flexible power supply architecture. TI recommends that the VDD_IN, VDD_PLL1, VDD_PLL2, and VDD_DIG supplies are driven by the same low-noise 3.3V supply rail, but the individual VDDO_x supplies can be driven from separate 1.8V, 2.5V, or 3.3V supply rails. Noise on the 3.3V supply rail can mix into the VCO through the VDD_PLLx pins. Take adequate layout precautions to reduce high frequency noise on the power pins. Lowest power consumption can be realized by operating the VDD_IN, VDD_PLL1, VDD_PLL2, and VDD_DIG supplies from a 3.3V rail and the VDDO_x supplies from a 1.8V rail. When using separate supplies, TI recommends using dedicated low-noise power supplies for the VDD and VDDO pins to mitigate issues stemming from leakage through the supply pins.