The AMC3336 is a fully differential, precision, isolated modulator with an integrated DC/DC converter that can supply the high-side of the device from a single 3.3-V or 5-V voltage supply on the low side. The input stage of the device drives a second-order, delta-sigma (ΔΣ) modulator. The modulator converts the analog input signal into a digital bitstream that is transferred across the isolation barrier and separates the high-side from the low-side. The isolated data output DOUT of the modulator provides a stream of digital ones and zeros that is synchronous to the externally-provided clock source at the CLKIN pin. The time average of this serial bitstream output is proportional to the analog input voltage. The external clock input simplifies the synchronization of multiple measurement channels on the system level.

The signal path is isolated by a double capacitive silicon dioxide (SiO₂) insuation barrier, whereas power isolation uses an on-chip transformer separated by a thin-film polymer as the insulating material.